Philippine Health Research Registry
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Results 1 - 10 of 10 research(es) registered in July 2016

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Study
         
Project Status:
Ongoing
Project Description:
DNA technology is the most powerful scientific tool for human identification. DNA profiling of biological samples such as tissues, e.g. bones, muscles; and body fluids such as blood, saliva, sweat and urine, is used to determine the human sources of these samples. In the present study, we propose to use this same technology to generate the autosoma... [read more]
Project Status:
Completed
Project Description:
Objective: The aim of the study was to determine if IHM-PG01 can inhibit the growth of Staphylococcus aureus in an animal model of nonfatal subcutaneous infection. Methodology: The minimum inhibitory concentration of IHM-PG01 against Methicillin sensitive Stapylococcus aureus, Methicillin resistant S. aureus,  and Streptococcus pyogenes was d... [read more]
Project Status:
Completed
Project Description:
Objective: The aim of the study is to determine if IHM-QA and IHM-MC have anti-ameba, antigiardia, antihelmintic or anti-malarial activity.Methodology: In vitro  models was used to measure the antiamebic, antigiardia and the antihelmintic (using C. elegans) activity E. hystolitica HK-9, G. intestinalis  and C. elegans were used in these mode... [read more]
Project Status:
Completed
Project Description:
Objective: To determine the effect of oral lyophilized aqueous IHM-BB on the intraocular pressure of steroid-induced ocular hypertensive rabbits. Methodology: A more concentrated lyophilized aqueous IHM-BB was used and was initially tested in a rabbit model. Dexamethasone sodium phosphate 0.1% eyedrops were applied on both eyes to induce ocular hy... [read more]
Project Status:
Ongoing
Project Description:
We are using combined experimental and computational methods to resolve the 3D structures of Venus Kinase Receptors (VKRs), potential drug targets against the locally endemic parasitic agent, Schistosoma japonicum, that causes the fatal disease Schistosomiasis.
Project Status:
Ongoing
Project Description:
To develop and validate methods for the preparation of chemical fingerprints and simultaneous quantification of marker compounds present in lagundi, sambong and tsaang gubat leaves and tablets using HPLC
Project Status:
Ongoing
Project Description:
The general objective of the study is to determine the bioactive secondary metabolites from the crude leaf extract and endophylic fungi through TLC bioautography against MRSA strains
Project Status:
Ongoing
Project Description:
multicenter, paired-eye, randomized, efficacy evaluator-masked 14-monthstudy
Project Status:
Ongoing
Project Description:
This is a trial of continuing sitagliptin versus withdrawing sitagliptin in participants with Type 2 diabetes mellitus (T2DM) and inadequate glycemic control who initiate and titrate insulin glargine (LANTUS®) based on a treat-to-target algorithm to achieve fasting glucose levels of 72-100 mg/dL (4-5.6 mmol/L). A primary hypothesis of this trial i... [read more]
Project Status:
Ongoing
Project Description:
New approaches are needed to achieve more rapid elimination of dormant mycobacteria and thereby shorten treatment for drug-sensitive and drug-resistant tuberculosis (TB). Dormant mycobacteria are relatively resistant to antibacterial drugs and approaches that enhance immune clearance have the potential to be more effective. Interleukin-4 (IL-4) is ... [read more]