i

EFFICACY OF DRY HYDROGEN PEROXIDE TECHNOLOGY IN REDUCING MICROBIAL COLONIZATION IN THE AIR AND HIGH TOUCH AREAS IN A TERTIARY HOSPITAL IN THE PHILIPPINES  

PHRR211202-004125

Unspecified

Unspecified

EFFICACY OF DRY HYDROGEN PEROXIDE TECHNOLOGY IN REDUCING MICROBIAL COLONIZATION IN THE AIR AND HIGH TOUCH AREAS IN A TERTIARY HOSPITAL IN THE PHILIPPINES

 

Isolation rooms in the hospital that have no proper ventilation may increase the possibility of more pathogenic microbes circulating in the air and hospital equipment that may transmit and be the cause of hospital acquired infections. Droplet nuclei that transmit TB infection have remained a concern because of the difficulties in detecting infectious MTB. The organisms are present in low concentrations in indoor air, slow growing (more than 6 weeks) and may be hard to do culture due to its aerosolization. 

A better understanding of what organisms are circulating in the Isolation Rooms while the patients are admitted would be able to evaluate the risk of the patients and their caregivers to these infectious agents. A devise such as DHP (Synexis TM) as an adjunct to regular cleaning of the rooms may be able to attempt to reduce exposure and control the disease.

Dry hydrogen peroxide technology is a new patented technology that utilizes ambient air to produce hydrogen peroxide as a near-ideal gas that has demonstrated potent disinfective activity against a variety of bacteria, fungi and viruses. The use of this devise could help in the infection control measures in the hospital setting without closing the unit/isolation rooms in between admissions and may help reduce hospital -acquired infections.

 

Regime Classification Priority
2017 - 2022 Global competitiveness and innovation in health Biomedical products and engineering
Start Date Duration in Months Target Completion Date Actual Completion Date
2022-02-01 4 2022-06-01 0000-00-00

Pending

Due to the pandemic, laboratory services were limited including limitations in the transport of the specimens

Institution Classification Region LTO #
Philippine General Hospital None Philippines
Institution Region
Pediatric Infectious Disease Society of the Philippines NCR
Name E-Mail Institution and Institution Address
Marimel R Pagcatipunan mrpagcatipunan@yahoo.com Philippine General Hospital, Taft Avenue, Manila
Name E-Mail Institution and Institution Address
Marimel R Pagcatipunan mrpagcatipiunan@yahoo.com Philippine General Hospital, Taft Avenue, Manila
Name Expertise Affiliation
Marimel R. Pagcatipunan, MD Pediatric Infectious Disease Philippine General Hospital
Project Location Institutional Ethics Review Board
Philippine General Hospital Philippine General Hospital Ethics Review Board

A better understanding of what organisms are circulating in the Isolation Rooms while the patients are admitted would be able to evaluate the risk of the patients and their caregivers to these infectious agents. A devise such as DHP (Synexis TM) as an adjunct to regular cleaning of the rooms may be able to attempt to reduce exposure and control the disease.

 

The primary objective of this study is to assess the efficacy of a DHP microbial reduction system (Synexis TM) as an adjunct to routine environmental cleaning and disinfection in reducing the degree of air and surface microbial contamination in select areas of the Department of Pediatrics and Internal Medicine of the Philippine General Hospital.

 

 

The secondary objectives are to determine the maximal efficacy of a DHP microbial reduction system (Synexis TM) in reducing air and surface microbial contamination by measuring bacterial colony counts when used over a specific time period, and to determine the duration of action of a DHP microbial reduction system (Synexis TM) in decreasing air and surface microbial contamination when use is discontinued over a specific time period.

Pending

Clinical Trial

Unspecified

Unspecified

0000-00-00

0000-00-00

10

Unspecified

Unspecified

0000-00-00

The principal investigators will obtain verbal and written consent from each patient and/or one or both parents or legal guardian upon admission to the isolation rooms of the identified units in the hospital. All patient information will be anonymized and kept confidential. 

 

Interventional

Dry Hydrogen Peroxide Machine

The study will be conducted in the isolation rooms of a public tertiary hospital over a period of 2 months (60 days).

 

None

Non-Randomized

Open Label

Unspecified

Crossover

The disinfection efficacy of Synexis TM DHP as an adjunct to routine environmental cleaning and disinfection will be superior to no Synexis TMDHP in reducing air and surface microbial levels in select areas of the hospital.

 

 

Phase II/III

Utilization Utilization Info
Publication

Pediatric Infectious Disease Society Journal

Oral Presentation

PIDSP convention 

Drug Literature
Posters
Others
©2022 HERDIN PLUS. All rights reserved. | Contact Us | Keep up to date