GlobalSurg-CovidSurg Week: Determining the optimal timing for surgery following SARS-CoV-2 infection – Philippine General Hospital data
PHRR220524-004693
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GlobalSurg-CovidSurg Week: Determining the optimal timing for surgery following SARS-CoV-2 infection
Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This study will contribute to the international, multicentre, prospective cohort study that included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre-operative SARS-CoV-2 infection were compared with those without previous SARS-CoV-2 infection. The primary outcome measure was 30-day postoperative mortality. Logistic regression models were used to calculate adjusted 30-day mortality rates stratified by time from diagnosis of SARS-CoV-2 infection to surgery.
| Regime | Classification | Priority |
|---|---|---|
| 2017 - 2022 | Responsive health systems | Emerging and re-emerging diseases |
| Start Date | Duration in Months | Target Completion Date | Actual Completion Date |
|---|---|---|---|
| 2022-10-01 | 12 | 2023-10-01 | 2022-12-01 |
Completed
| Institution | Classification | Region | LTO # |
|---|---|---|---|
| Philippine General Hospital | None | Philippines |
| Institution | Region |
|---|---|
| Philippine General Hospital | Philippines |
| Name | Institution and Institution Address | |
|---|---|---|
| Marie Dione P. Sacdalan | maparrenosacdalan@up.edu.ph | Philippine General Hospital, Taft Avenue, Ermita, Manila |
| Name | Institution and Institution Address | |
|---|---|---|
| Marie Dione P. Sacdalan | maparrenosacdalan@up.edu.ph | Philippine General Hospital, Taft Avenue, Manila |
| Name | Expertise | Affiliation |
|---|---|---|
| Ryle Ong Li | General Surgery | Philippine General Hospital |
| Vincent Abad Venida | General Surgery | Philippine General Hospital |
| Project Location | Institutional Ethics Review Board |
|---|---|
| Philippine General Hospital | Philippine General Hospital Ethics Review Board |
| Philippine General Hospital | Philippine General Hospital Ethics Review Board |
COVID19
30 day Post-operative Mortality
Optimal timing of surgery following SARSCoV2 Infection
Completed
Clinical Trial
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300
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The inclusion criteria are:
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● Any operations (elective or emergency) done in an operating theater by a surgeon,
excluding minor procedures previously defined by Abbott, et. al [7] (see Appendix A).
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● All surgical specialties including: acute care surgery, breast surgery, cardiac surgery, colorectal surgery, general surgery, gynecology, hepatobiliary surgery, neurosurgery,
obstetrics, esophagogastric surgery, ophthalmology, oral and maxillofacial surgery, orthopedics, otolaryngology, pediatric surgery, plastic surgery, thoracic surgery, transplant surgery, trauma surgery, urology, vascular surgery.
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● Day case surgery and inpatient surgery is included
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● Any SARS-CoV-2 status (positive at any time, negative, not tested)
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● All ages including children and adults
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Observational
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None
Non-Randomized
N/A
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Not Applicable
To determine the optimal timing for surgery following SARS-CoV-2 infection by comparing mortality rates between patients preoperatively infected with SARS-CoV-2, those who had an infection perioperatively, and those presumed to be unexposed at the time of surgery.
Not Applicable